Levetiracetam, Phenytoin, and Valproate Act Differently on Rat Bone Mass, Structure, and Metabolism
نویسندگان
چکیده
منابع مشابه
How can antiepileptic drugs affect bone mass, structure and metabolism? Lessons from animal studies
Patients with epilepsy, treated with antiepileptic drugs (AEDs) are at increased risk of fractures. Although several commonly used AEDs reduce bone mass in patients, the mechanisms are only scarcely known. In this review, we focus on the usefulness of animal models to explore the skeletal effects of AEDs. Moreover, we report our findings from a recent study comparing the effect of levetiracetam...
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15 صفحه اولEfficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery.
BACKGROUND Antiepileptic drugs are routinely given after craniotomy. Though phenytoin (PHT) is still the most commonly used agent, levetiracetam (LEV) is increasingly administered for this purpose. This retrospective study compared the use of LEV and PHT as monotherapy prophylaxis following supratentorial neurosurgery. METHODS Patients receiving LEV monotherapy after supratentorial craniotomy...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2007
ISSN: 0013-9580,1528-1167
DOI: 10.1111/j.1528-1167.2007.01176.x